In this article, Luciano Attolico discusses the consequences of supply chain digitization. Attolico states that digitization is not sufficient to ensure the balance between economic sustainability and human sustainability. To achieve the balance and obtain the best results, Attolico proposes business management based on three elements: a holistic approach within the organization, increased awareness among partners, and increased flexibility in process management. To support his thesis, Attolico offers a series of concrete examples drawn from companies that have achieved success in implementing these solutions. This article offers a general and practical overview of the topic, providing valuable suggestions on how to manage supply chains in a more sustainable way from both an economic and human perspective.